Admissibility in Partial Conjunction Testing
نویسندگان
چکیده
منابع مشابه
Admissibility in Partial Conjunction Testing
Meta-analysis combines results from multiple studies aiming to increase power in finding their common effect. It would typically reject the null hypothesis of no effect if any one of the studies shows strong significance. The partial conjunction null hypothesis is rejected only when at least r of n component hypotheses are non-null with r = 1 corresponding to a usual meta-analysis. Compared wit...
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The partial conjunction (PC) alternative hypothesis H r/n 1 stipulates that at least r of n related basic hypotheses are non-null, making it a useful measure of replicability. Motivated by genomic problems we consider a setting with a large number M of partial conjunction null hypotheses to test, based on an n×M matrix of p-values. When r > 1 the hypothesis H 0 is composite. Validity versus the...
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SUMMARY We consider the problem of testing for partial conjunction of hypothesis, which argues that at least u out of n tested hypotheses are false. It offers an in-between approach to the testing of the conjunction of null hypotheses against the alternative that at least one is not, and the testing of the disjunction of null hypotheses against the alternative that all hypotheses are not null. ...
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ژورنال
عنوان ژورنال: Journal of the American Statistical Association
سال: 2018
ISSN: 0162-1459,1537-274X
DOI: 10.1080/01621459.2017.1385465